Playing Lead Guitar--Pentatonic Minor Scales

If the key is in G, can I also play over the C position on the 8th fret? This would be 12 bar blues using the minor pentatonic scale.

ANSWER

No, you cannot use the C pentatonic minor scale when playing in the key of G.

The notes in the C pentatonic minor scale are C Eb F G Bb.

The notes in the I IV V progression are GBE SEG
and DF#A.

As you can see, the Eb, F, and Bb of the C pentatonic minor scale are in serious conflict with the notes in the chords you are using.

The correct pentatonic minor scales for a I IV V progression in G are G pentatonic minor and E pentatonic minor.

Lynne